When visiting Plaza Botero, it’s best to wear comfortable shoes as you’ll likely be walking around and exploring the area. The plaza can get crowded, particularly on weekends, so be prepared for busy scenes. Be cautious of your personal belongings, as the area can attract pickpockets, especially in the more tourist-heavy spots. Although the square itself is free to visit, some of the sculptures may be roped off for safety, and additional fees may apply for museum entry or guided tours.

Plaza Botero is centrally located in Medellín, making it easy to reach from most areas of the city. The most convenient way to get there is by Metro. Take Line A (the green line) and get off at Parque Berrío station, which is just a short walk from the plaza. Alternatively, you can take a taxi or Uber, especially if you're staying in the El Poblado area, which is about a 10-minute drive from the square. The plaza is also easily accessible from La 70 and Pueblito Paisa.

The best time to visit Plaza Botero is during the day, as the sculptures are best appreciated under natural light. Early mornings or weekdays are ideal for a quieter experience, while weekends may be busier with both locals and tourists. If you're planning to visit the Museo de Antioquia, you can combine your visit to the museum and plaza in the same trip. Evenings can be lively, especially with the surrounding area's restaurants and cafes coming to life, but the plaza itself may feel quieter at night.

Plaza Botero is an excellent destination for a half-day or full-day trip from your base in Medellín. After visiting the plaza, take a short walk to explore the Museo de Antioquia, which houses a more extensive collection of Botero’s art and other significant works. You can also explore Parque de las Luces (Park of Lights) nearby, which is a popular spot for a relaxed stroll in the evening. For more art, head to the Casa de la Memoria museum, which tells the story of Medellín's history. The area around Plaza Botero is rich in culture, making it easy to spend a day exploring nearby attractions.