Photography is typically not allowed inside, so be prepared to savor the beauty of the synagogue without snapping pictures. The museum exhibits are well-documented in English, making it easy for international visitors to understand the displays. Wear comfortable shoes, as you’ll likely explore other sites in Josefov. The synagogue is wheelchair accessible.

The Spanish Synagogue is located in central Prague and is easily accessible by public transport. The nearest metro station is "Staroměstská" (Line A), just a 5-minute walk away. Tram lines 17 and 18 also stop nearby. If you’re exploring Prague’s Old Town, the synagogue is a short walk from the Old Town Square.

The Spanish Synagogue is open year-round, but it is closed on Saturdays and Jewish holidays. Weekday mornings and early afternoons are generally less crowded, making it a great time for a quieter visit. Visiting during one of the evening concerts held in the synagogue offers a magical experience, as the acoustics and setting provide a memorable atmosphere.

The Spanish Synagogue is best visited as part of a larger tour of the Jewish Quarter. Combine it with nearby attractions like the Old-New Synagogue, the Jewish Cemetery, and the Jewish Museum. Afterward, enjoy a meal at a nearby café or restaurant that specializes in traditional Czech or kosher cuisine. The synagogue’s location in the Old Town makes it easy to incorporate into your day of exploring Prague’s historic core.